Bone cement distribution is a potential predictor to the reconstructive effects of unilateral percutaneous kyphoplasty in OVCFs: a retrospective study

Bone cement distribution is a potential predictor to the reconstructive effects of unilateral percutaneous kyphoplasty in OVCFs: a retrospective study

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Abstract Background Osteoporotic vertebral compression fracture (OVCF) is a common type of fracture, and percutaneous kyphoplasty (PKP) is an eligible solution to it.Previous studies have revealed that both the volume and filling pattern of bone cement correlate with the clinical outcomes after PKP procedure.However, the role of bone cement distribution remains to be illustrated.Methods To retrospectively evaluate the relationship between the bone cement distribution and the clinical outcomes of unilateral PKP, we enrolled 73 OVCF patients receiving unilateral PKP treatment.All the intervened vertebrae were classified into three groups based on the bone cement distribution observed on postoperative X-ray films.

Preoperative and postoperative radiographic parameters including the vertebral height and kyphotic Cobb angle were recorded, and anterior vertebral height restoration rate (AVHRR) and Cobb angle correction (CR) were then calculated to assess the vertebral height reconstruction.Preoperative and postoperative Oswestry Disability Index (ODI) and visual Arm and Leg Protection analogue scale (VAS) were adopted by interviewing patients to assess the mobility improvement and pain relief.Demographic data, body mass index (BMI), lumbar bone mineral density (evaluated by BMD T-score) of each patient, bone cement volume (BV), and bone cement extravasation (BE) were also recorded.Between- and within-group comparisons and multivariable correlation analysis were carried out to analyze the data.Results VAS and ODI scores were both significantly improved in all of the enrolled cases with no significant differences between groups.

Among the three groups, the average age, AVHRR, and BV were significantly different.Occurrence of BE was significantly different between two of the three groups.AVHRR was demonstrated to correlate negatively with preoperative anterior vertebral height ratio and positively with preoperative Cobb angle, CR, diffusion score, and ODI changes.Conclusions CONDIMENT DEUO Bone cement distribution is a potential predictor to the reconstructive effects in unilateral PKP for OVCFs.Bone cement distribution is associated with AVHRR and BV, as well as the risk of BE occurrence.

Greater bone cement distribution may indicate better vertebral restoration along with a higher BE risk.